Taurine 4 : Taurine and Excitable Tissues

Language: English

Published by Springer, 2013

1475773420 / 9781475773422

Series: Book 10 of 544 - Advances in Experimental Medicine and Biology

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Druck auf Anfrage Neuware - Printed after ordering - Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the 'setpoint' andcorresponds to values between 0.3-3µM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. membrane potential. pH gradient. Adapted from .

Seller Inventory # 9781475773422

Title
Taurine 4 : Taurine and Excitable Tissues
Author
Keith F. Tipton
Publisher
Springer
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
1475773420
ISBN 13
9781475773422
Item weight
1,013 grams
Dimensions
235x155x37 mm
Series
Book 10 of 544: Advances in Experimental Medicine and Biology

AHA-BUCH GmbH

Einbeck, Germany

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