TGF-Beta Family, Second Edition
Language: English
Published by Cold Spring Harbor Laboratory Press CSHL Press, 2017
Series: Book 2 of 42 - Perspectives CSHL
- Hardcover
- New
Seller: Books Puddle, Woodside, NY, U.S.A.Books Puddle
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- Title
- TGF-Beta Family, Second Edition
- Author
- Derynck, Rik; Miyazono, Kohei
- Publisher
- Cold Spring Harbor Laboratory Press CSHL Press
- Publication year
- 2017
- Condition
- New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 162182036X
- ISBN 13
- 9781621820369
- Series
- Book 2 of 42: Perspectives CSHL
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive view of the different members of the TGF- family, the signaling pathways they control, and how they influence development, normal physiology, and disease. The contributors describe the various TGF- family ligands, including activins and bone morphogenetic proteins (BMPs), the structures and functions of the type I and type II receptors, and how ligand-receptor binding is regulated. Both Smad and non-Smad signaling pathways are discussed, as is cross talk between TGF- and other signaling pathways (e.g., Wnt). Individual chapters are devoted to the roles of TGF- signaling in specific biological processes, including cell proliferation, mesenchymal differentiation, branching morphogenesis, stem cell biology, immunity, vascular function, reproduction, and neurobiology. The roles of TGF- signaling in cancer, fibrosis, skeletal diseases, and other conditions, as well as prospects for therapeutics, are also covered.
The authors also review TGF- signaling in model organisms (e.g., C. elegans and Drosophila), as well as the discovery of TGF- and early research in the field. This volume is therefore a comprehensive reference on the biology of the TGF- family, and it will be valuable for not only cell and developmental biologists but all who wish to learn about this important field of research.
"Synopsis" may belong to another edition of this title.
Books Puddle
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