Systme de libration de mdicament bioadhsif flottant base d'amoxicilline trihydrate (Paperback)
Published by Editions Notre Savoir, 2025
- Softcover
- New
Seller: Grand Eagle Retail, Bensenville, IL, U.S.A.Grand Eagle Retail
AbeBooks seller since October 12, 2005
Condition: New
£ 39.35
Quantity: 1 available
Add to basketItem description from seller
Paperback. La presente etude avait pour objectif de formuler et d'evaluer des comprimes bioadhesifs flottants a base d'amoxicilline trihydratee (ATFBT) afin d'obtenir une action locale dans le traitement de Helicobacter Pylori (H. Pylori) en prolongeant le temps de sejour dans l'estomac. Les FBT ont ete prepares par compression directe en utilisant une combinaison d'hydroxypropylmethylcellulose (HPMC K4M) et de chitosane (CH), de carbopol (CP974P) et d'acide polymethacrylique (PMA) comme retardateurs de liberation et polymeres bioadhesifs, et de bicarbonate de sodium (NaHCO3) comme agent gazogene. Les comprimes prepares ont ete evalues pour leurs caracteristiques physiques telles que la teneur en medicament, la flottabilite in vitro, l'indice de gonflement, la liberation in vitro du medicament et la stabilite. De plus, la force bioadhesive (BS) a ete determinee a l'aide de muqueuse gastrique porcine. Les etudes DSC indiquent la compatibilite du medicament et des excipients utilises dans la formulation. La formulation optimisee (F7) a montre un temps de flottement de 32 2,7 secondes, un temps de flottement total superieur a 12 heures, une BS de 1,86 0,14 N, un indice de gonflement superieur a 3,5 et s'est revelee physiquement stable lorsqu'elle a ete conservee a 40 0C/75 % d'humidite relative pendant 3 mois. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…
Seller Inventory # 9786208888169
- Title
- Systme de libration de mdicament bioadhsif flottant base d'amoxicilline trihydrate (Paperback)
- Author
- Ramesh Bomma
- Publisher
- Editions Notre Savoir
- Publication year
- 2025
- Condition
- new
- Binding
- Paperback
- ISBN 10
- 6208888166
- ISBN 13
- 9786208888169
"Synopsis" may belong to another edition of this title.
Grand Eagle Retail
Bensenville, IL, U.S.A.
AbeBooks seller since October 12, 2005
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| Item | 6 to 14 business days | 6 to 16 business days |
|---|---|---|
| First item | £ 0.00 | £ 0.00 |
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