Systems Biology: Modeling Analysis and Simulation

Lei, Jinzhi

ISBN 10: 3030730328 / ISBN 13: 9783030730321

Published by Springer, 2021

This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide. Seller Inventory # ABBB-40348

Synopsis:

This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration. The diffusion of morphogens is addressed by introducing various reaction-diffusion equations based on different hypotheses concerning the process of morphogen gradient formation. The robustness of steady-state gradients is also covered through boundary value problems.

The introduction gives an overview of the relevant biological concepts (cells, DNA, organism development) and provides the requisite mathematical preliminaries on continuous dynamics and stochastic modeling. A basic understanding of calculus is assumed.

The techniques described in this book encompass a wide range of mechanisms, from molecular behavior to population dynamics, and the inclusion of recent developments in the literature together with first-hand results make it an ideal reference for both new students and experienced researchers in the field of systems biology and applied mathematics.

About the Author: Jinzhi Lei (Ph.D. 2001, Beihang University) is Professor at the School of Mathematical Sciences, Tiangong University, China. He was a postdoc at UC, Irvine (2004–2005) and Associate Researcher at the Zhou Pei-Yuan Center for Applied Mathematics, Tsinghua University, China (2006–2019). His research focuses on modeling dynamical blood diseases, cancer development and stem cell regeneration.

Bibliographic Details

Title: Systems Biology: Modeling Analysis and ...
Publisher: Springer
Publication Date: 2021
Binding: Soft cover
Condition: New