Systems Biology of Cell Signaling : Recurring Themes and Quantitative Models
Language: English
Published by Taylor & Francis Ltd Sep 2021, 2021
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
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Neuware - This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing upon modeling, theory and experimentation. It seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools needed to apply modeling/theory to biological processes.
Seller Inventory # 9780367643836
- Title
- Systems Biology of Cell Signaling : Recurring Themes and Quantitative Models
- Author
- James (Stanford University Ferrell
- Publisher
- Taylor & Francis Ltd Sep 2021
- Publication year
- 2021
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 0367643839
- ISBN 13
- 9780367643836
- Item weight
- 690 grams
- Dimensions
- 254x203x0 mm
How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes.
Key Features:
- Full-color illustration program with diagrams to help illuminate the concepts
- Enables the reader to apply modeling and theory to the biological processes
- Further Reading for each chapter
- High-quality figures available for instructors to download
"Synopsis" may belong to another edition of this title.
About the Author
James E. Ferrell, Jr., MD, PhD is Professor of Chemical and Systems Biology and Professor of Biochemistry at Stanford. His work, which makes use of quantitative experimental approaches, modeling and theory, looks to understand the design principles of biochemical switches, timers, and oscillators, especially those that control the cell cycle.
"About the title" may belong to another edition of this title.
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