Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application
Language: English
Published by Springer Nature Singapore, Springer Nature Singapore, 2018
- Hardcover
- New

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- Title
- Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application
- Author
- Youngjun Lee
- Publisher
- Springer Nature Singapore, Springer Nature Singapore
- Publication year
- 2018
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 9811316449
- ISBN 13
- 9789811316449
- Item weight
- 494 grams
- Dimensions
- 241x160x18 mm
- Series
- Book 498 of 797: Springer Theses
Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working underlive cell conditions.
Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.
"Synopsis" may belong to another edition of this title.
About the Author
Dr. Youngjun Lee is a member of CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Korea. He earned Ph.D. degree in organic chemistry at SNU in February 2018.
"About the title" may belong to another edition of this title.
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