Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application

Language: English

Published by Springer Nature Singapore, Springer Nature Singapore, 2018

9811316449 / 9789811316449

Series: Book 498 of 797 - Springer Theses

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Druck auf Anfrage Neuware - Printed after ordering - This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter.Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working underlive cell conditions.Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

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Title
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules : Synthesis, Analysis and Application
Author
Youngjun Lee
Publisher
Springer Nature Singapore, Springer Nature Singapore
Publication year
2018
Condition
Neu
Binding
Buch
Language
English
ISBN 10
9811316449
ISBN 13
9789811316449
Item weight
494 grams
Dimensions
241x160x18 mm
Series
Book 498 of 797: Springer Theses

AHA-BUCH GmbH

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