Synthese von Vancomycinsonden für Activity-Based Protein Profiling
Language: German
Published by GRIN Verlag, 2011
- Softcover
- Used
Seller: Buchpark, Trebbin, GermanyBuchpark
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Condition: Used - Fine
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Add to basketItem description from seller
Zustand: Sehr gut | Seiten: 56 | Sprache: Deutsch | Produktart: Bücher | Bachelorarbeit aus dem Jahr 2008 im Fachbereich Chemie - Organische Chemie, Note: 1.7, Ludwig-Maximilians-Universität München, Sprache: Deutsch, Abstract: In den letzten Jahren kamen Hinweise auf, dass Chlorbiphenyl-Derivate von Vancomycin direkt Proteine blockieren, die an der Peptidoglycan-Synthese beteiligt sind. Einige solcher Proteine, die PBPs konnten schon in der Membranfraktion von E. coli identifiziert werden. Ziel dieser Arbeit ist es, weitere zelluläre Angriffsziele von Chlorbiphenyl-Derivaten von Vancomycin zu finden. Hierzu wurde die Methode des Activity Based Protein Profiling (ABPP) angewandt. Es wurden mehrere Sonden mit unterschiedlichem Aufbau synthetisiert und an den Proteomen der Gram-positiven Bakterien B. subtilis, Listeria welshimeri und Bacillus licheniformis sowie der Gram-negativen Bakterien Pseudomonas putida und Escherichia coli getestet.
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- Title
- Synthese von Vancomycinsonden für Activity-Based Protein Profiling
- Author
- Pochorovski, Igor
- Publisher
- GRIN Verlag
- Publication year
- 2011
- Condition
- Sehr gut
- Binding
- Soft cover
- Language
- German
- ISBN 10
- 3640965256
- ISBN 13
- 9783640965250
- Seller catalogs
- Bücher
"Synopsis" may belong to another edition of this title.
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