The Synapse : Structure and Function
Language: English
Published by Elsevier Science, 2013
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 133.93
Quantity: 2 available
Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings.…
Seller Inventory # 9780124186750
- Title
- The Synapse : Structure and Function
- Author
- Menahem Segal
- Publisher
- Elsevier Science
- Publication year
- 2013
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 0124186750
- ISBN 13
- 9780124186750
- Item weight
- 1,265 grams
- Dimensions
- 241x195x30 mm
"Synopsis" may belong to another edition of this title.
About the Author
I was born on August 11, 1944, towards the end of WWII. My early life memories include running for a shelter to the sound of the sirens, as the Egyptians were bombing Tel Aviv, during the war of 1948. I grew up in Israel, went to school at a local university, and was one of the earliest students to combine Experimental Psychology and Biology. After graduating with a MS degree, I realized that Neuroscience education was non-existent at the time in Israel, and decided to obtain it in the US. I was fortunate to be accepted to graduate studies at Cal Tech, under the supervision of the late Jim Olds, an amazing educational and personal experience. From there I went for a Postdoc position with Floyd Bloom, then at the NIMH. These were the early days of Neuroscience, quite exciting, indeed. This was a transition period from the old paper electrophysiology, with EPSP counts on a Grass camera, to the modern world, and personal computers were about to be invented. My next critical decision was in 1974, to go back to Israel and take a position at the Weizmann Institute, where I have been working since. I could have done better, I could have done worse, but I like what I am doing, studying plasticity in cultured neurons and brain slices, combining electrophysiology and imaging of living dendritic spines. It is fun.
"About the title" may belong to another edition of this title.
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