Stem Cell Proliferation and Differentiation

Language: English

Published by Springer, Springer Vieweg Okt 1988, 1988

3540501835 / 9783540501831

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This item is printed on demand - Print on Demand Titel. Neuware -The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 128 pp. Englisch.

Seller Inventory # 9783540501831

Title
Stem Cell Proliferation and Differentiation
Author
Catherine A. Macken
Publisher
Springer, Springer Vieweg Okt 1988
Publication year
1988
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3540501835
ISBN 13
9783540501831
Item weight
236 grams
Dimensions
244x170x8 mm

buchversandmimpf2000

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