This book is the third revised and updated English edition of the German textbook \Versuchsplanung und Modellwahl" by Helge Toutenburg which was based on more than 15 years experience of lectures on the course \- sign of Experiments" at the University of Munich and interactions with the statisticians from industries and other areas of applied sciences and en- neering. This is a type of resource/ reference book which contains statistical methods used by researchers in applied areas. Because of the diverse ex- ples combined with software demonstrations it is also useful as a textbook in more advanced courses, The applications of design of experiments have seen a signi?cant growth in the last few decades in di?erent areas like industries, pharmaceutical sciences, medical sciences, engineering sciences etc. The second edition of this book received appreciation from academicians, teachers, students and applied statisticians. As a consequence, Springer-Verlag invited Helge Toutenburg to revise it and he invited Shalabh for the third edition of the book. In our experience with students, statisticians from industries and - searchers from other ?elds of experimental sciences, we realized the importance of several topics in the design of experiments which will - crease the utility of this book. Moreover we experienced that these topics are mostly explained only theoretically in most of the available books.

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This textbook presents the design and analysis of experiments that comprise the aspects of classical theory for continuous response, modern procedures for categorical response, and especially for correlated categorical response. For any design (independent and matched-pair response) the parametric and nonparametric tests depending on the data level are given. Complex designs, such as, for example, cross-over and repeated measures, are included at an introductory and advanced manner. The problem of missing data is also handled with care and procedures in approaching this problem are proposed. Thus, this is an important resource/reference book for undergraduates and university teachers, for statistical researchers in the pharmaceutical industry, or other industries, as well as for clinical research in medicine and dentistry.

The third edition contains a new chapter on incomplete block designs that includes the balanced incomplete block design and partially balanced incomplete block design in addition to the general theory on incomplete block designs. The chapter "Multifactor Experiments" is extended and includes new topics on confounding, partial confounding and fractional replications that are explained with examples. The more theoretical proofs of Chapters 3, 4 and 6 are put into an appendix.

Helge Toutenburg is Professor of Statistics at the University of Munich. He has written nineteen books on linear models, statistical methods in quality engineering, and the analysis of designed experiments. He works on applications of statistics to the fields of medicine and engineering.

Shalabh is Associate Professor of Statistics at the Indian Institute of Technology Kanpur. He has co-authored a book on linear models and co-edited a book on the recent developments in the area of linear models. He works in the area of linear models, regression analysis and econometrics.

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