Stable Feature Selection in Empty Spaces : Applications to Gene Profiling and Diagnosis from DNA Microarrays

Language: English

Published by LAP LAMBERT Academic Publishing, 2011

3844390146 / 9783844390148

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Many technological fields produce data characterised by a steadily growing number of dimensions. That number is however often growing much faster than the number of points available. A typical illustration of this trend is Genomics. This setting makes many machine learning applications subject to the curse of dimensionality, making difficult the estimation of robust predictive models. This book focuses on the design and application of techniques achieving both sparse feature selection and estimation of models with good classification performance in high-dimensional, empty spaces. This challenge can be successfully addressed provided that adequate inductive biases are used to mitigate the lack of extra samples. Those biases can consist either of taking many different views of the data only (ensemble methods), or of the use of external extra information, either field expert prior knowledge or other datasets about related tasks (transfer learning or multi-task learning). The proposed methods are tested over gene expression microarray datasets for diagnosis and biomarker discovery. Those datasets are typically made of few tens of samples (patients) and thousands of dimensions (genes).

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Title
Stable Feature Selection in Empty Spaces : Applications to Gene Profiling and Diagnosis from DNA Microarrays
Author
Thibault Helleputte
Publisher
LAP LAMBERT Academic Publishing
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3844390146
ISBN 13
9783844390148
Item weight
417 grams
Dimensions
220x150x17 mm

AHA-BUCH GmbH

Einbeck, Germany

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