Solute Carrier Protein Family (Paperback)

Fatma Akin

ISBN 10: 6209390048 / ISBN 13: 9786209390043

Published by LAP Lambert Academic Publishing, 2025

Paperback. Selective transport mechanisms across the cell membrane are essential for maintaining cellular integrity and physiological balance. Drug transport proteins (DCPs) mediate the movement of endogenous molecules and therapeutic agents into and out of cells. These proteins are highly expressed in the liver, kidneys, brain, and intestines, where they regulate key cellular functions. Substances such as sugars, amino acids, vitamins, neurotransmitters, and xenobiotics are transported through these mechanisms, preserving physiological balance and protecting cells from harmful compounds. The solute carrier (SLC) protein family directly influences drug absorption, distribution, metabolism, and excretion, thereby affecting therapeutic efficacy, toxicity, and drug-drug interactions. Transporter expression and activity are modulated by genetic, physiological, and environmental factors. Recent molecular and pharmacogenetic studies show that SLC transporters contribute to disease pathophysiology and represent promising therapeutic targets, highlighting the importance of research and clinical practice.We hope this book will serve as a valuable guide for researchers. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9786209390043

Synopsis:

Selective transport mechanisms across the cell membrane are essential for maintaining cellular integrity and physiological balance. Drug transport proteins (DCPs) mediate the movement of endogenous molecules and therapeutic agents into and out of cells. These proteins are highly expressed in the liver, kidneys, brain, and intestines, where they regulate key cellular functions. Substances such as sugars, amino acids, vitamins, neurotransmitters, and xenobiotics are transported through these mechanisms, preserving physiological balance and protecting cells from harmful compounds. The solute carrier (SLC) protein family directly influences drug absorption, distribution, metabolism, and excretion, thereby affecting therapeutic efficacy, toxicity, and drug–drug interactions. Transporter expression and activity are modulated by genetic, physiological, and environmental factors. Recent molecular and pharmacogenetic studies show that SLC transporters contribute to disease pathophysiology and represent promising therapeutic targets, highlighting the importance of research and clinical practice.We hope this book will serve as a valuable guide for researchers.

Bibliographic Details

Title: Solute Carrier Protein Family (Paperback)
Publisher: LAP Lambert Academic Publishing
Publication Date: 2025
Binding: Paperback
Condition: new