In Silico and in Vitro Aldose Reductase Inhibition of Flavonoids (Paperback)

Language: English

Published by LAP Lambert Academic Publishing, 2026

6209863264 / 9786209863264

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Paperback. Cataracts are one of the primary causes of visual impairment in diabetics. Patients with diabetes mellitus are said to be five times more likely to acquire cataracts, particularly if they begin the condition early. Flavonoids are bioactive secondary metabolites of plants that belong to a large family of low molecular weight compounds and have a polyphenolic structure. This comprehensive book explores the therapeutic potential of novel flavonoid derivatives in combating diabetic cataractogenesis. Utilizing a multi-disciplinary approach, the research integrates in silico molecular docking to identify high-affinity aldose reductase inhibitors (ARIs) with traditional chemical synthesis and characterization techniques. The core of the investigation lies in a rigorous in vitro evaluation using isolated goat lenses, demonstrating how these specialized compounds retard lens opacification and mitigate oxidative stress. This book provides a critical scaffold for the development of non-surgical, plant-derived pharmacological interventions for vision preservation. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

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Title
In Silico and in Vitro Aldose Reductase Inhibition of Flavonoids (Paperback)
Author
M. Vijayabaskaran
Publisher
LAP Lambert Academic Publishing
Publication year
2026
Condition
new
Binding
Paperback
Language
English
ISBN 10
6209863264
ISBN 13
9786209863264

CitiRetail

Stevenage, United Kingdom

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