Sequence Alignment: Methods, Models, Concepts, and Strategies

Rosenberg Michael, S.:

ISBN 10: 0520256972 / ISBN 13: 9780520256972

Published by University of California Press, 2009

About this Item

Seiten; 9780520256972.3 Gewicht in Gramm: 1. Seller Inventory # 707609

Bibliographic Details

Title: Sequence Alignment: Methods, Models, ...

Publisher: University of California Press

Publication Date: 2009

Binding: hardcover

Condition: Gut

About this title

Synopsis:

The sequencing of the human genome involved thousands of scientists but used relatively few tools. Today, obtaining sequences is simpler, but aligning the sequences - making sure that sequences from one source are properly compared to those from other sources - remains a complicated but underappreciated aspect of comparative molecular biology. This volume, the first to focus on this crucial step in analyzing sequence data, is about the practice of alignment, the procedures by which alignments are established, and more importantly, how the outcomes of any alignment algorithm should be interpreted. Edited by Michael S. Rosenberg with essays by many of the field's leading experts, "Sequence Alignment" covers molecular causes, computational advances, approaches for assessing alignment quality, and philosophical underpinnings of the algorithms themselves.

About the Author:

Michael S. Rosenberg is Associate Professor of Computational Evolutionary Biology and Bioinformatics in the School of Life Sciences and the Center for Evolutionary Functional Genomics of the Biodesign Institute at Arizona State University.