STUDIO RP- HPLC DI REBAMIPIDE
Language: Italian
Published by Edizioni Sapienza Mrz 2021, 2021
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 34.66
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Lo scopo del presente lavoro è stato quello di sviluppare e convalidare un semplice metodo RP-HPLC per la determinazione di Rebamipide. La separazione cromatografica di Rebamipide è stata ottenuta utilizzando una colonna C18. Una fase mobile contenente una miscela di metanolo: acqua (70:30 v/v) è stata pompata alla velocità di flusso di 1 ml/min. La rilevazione è stata eseguita a 231 nm. I parametri di convalida sono stati valutati secondo le linee guida dell'International Conference on Harmonization (ICH) Q2R1. La curva di calibrazione è risultata lineare nell'intervallo di concentrazione 2- 10¿g/ml per la Rebamipide con coefficiente di regressione 0,999. Il metodo è risultato accurato con lo 0,66% RSD. I valori RSD sono risultati essere 0,94% nel caso degli studi di precisione intra-day, mentre 0,76% nel caso della precisione intra-day i limiti di rilevazione e quantificazione sono risultati essere 0,6, 1,98¿g/ml, rispettivamente. I risultati ottenuti dallo stress test rivelano che la sostanza farmacologica Rebamipide è particolarmente stabile in condizioni di degradazione acida, neutra e termica. Dal punto di vista della stabilità, occorre prestare attenzione nel processo di produzione e nello stoccaggio di questo prodotto. Il metodo è stato applicato con successo per la quantificazione ed è stato trovato t 64 pp. Italienisch. …
Seller Inventory # 9786203395532
- Title
- STUDIO RP- HPLC DI REBAMIPIDE
- Author
- Biswajit Samantaray
- Publisher
- Edizioni Sapienza Mrz 2021
- Publication year
- 2021
- Condition
- Neu
- Dust jacket
- Dust Jacket Included
- Binding
- Taschenbuch
- Language
- Italian
- ISBN 10
- 6203395536
- ISBN 13
- 9786203395532
- Item weight
- 113 grams
- Dimensions
- 220x150x4 mm
"Synopsis" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
Shipping rates from Germany to U.S.A.
| Item | 5 to 15 business days | 5 to 15 business days |
|---|---|---|
| First item | £ 19.39 | £ 19.39 |
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BuchWeltWeit Ludwig Meier e.K.
Germany
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