Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance and Methods of Delivery
Language: English
Published by Academic Pr, 2025
- Hardcover
- New
Seller: Revaluation Books, Exeter, United KingdomRevaluation Books
AbeBooks seller since January 6, 2003
Condition: New
£ 198.72
Quantity: 1 available
Add to basketItem description from seller
216 pages. 9.25x7.50x9.61 inches. In Stock.
Seller Inventory # x-044322305X
- Title
- Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance and Methods of Delivery
- Author
- Ghavami, Saeid (Editor)/ Zarrabi, Ali (Editor)/ Cordani, Marco (Editor)
- Publisher
- Academic Pr
- Publication year
- 2025
- Condition
- Brand New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 044322305X
- ISBN 13
- 9780443223051
- Item weight
- 0.98 kilograms
Retinoic Acids in Cancer Therapy: Mechanisms of Sensitivity, Resistance, and Methods of Delivery provides an overview of how All-Trans Retinoic Acid (ATRA) kills cancer cells and how some cells survive treatment. Focusing on the cellular pathways and compartments involved in ATRA-mediated inhibition of proliferation, this book also discusses how aggressive tumors develop escape routes conferring retinoic acid resistance.
Across 15 chapters, it describes the molecular structure and biological properties of ATRA, explains mechanisms of resistance, and defines ATRA’s efficacy in seven cancer types. It concludes with chapters on ATRA and cancer stem cell biology, strategies to improve treatment, future therapeutic perspectives, and delivery methods to reduce toxicity and enhance anticancer efficacy.
Each chapter includes Learning Objectives and a “What We Learn” section, making the book highly accessible for undergraduate, graduate trainees, scientists, physicians, and biotech companies. Adding simple, attractive schemes and informative tables makes it ideal for all interested in the current status of Retinoic Acids in Cancer Therapy. This book serves as a valuable resource for health professionals, scientists, researchers, clinical practitioners, and all those seeking to broaden their knowledge and develop new drugs or therapeutic strategies to improve ATRA’s efficacy in the treatment of resistant cancers.
- Includes Learning Objectives and “What We Learn” sections in every chapter
- Presents concise schematic figures illustrating apoptotic and autophagic pathways
- Explains the interplay of apoptosis (intrinsic and extrinsic) and autophagy in ATRA-induced cell death
- Discusses autophagy targeting to enhance ATRA effectiveness
- Examines cancer stem cell fate modulation with ATRA
- Highlights future directions and delivery strategies to minimize off-target effects
"Synopsis" may belong to another edition of this title.
About the Author
Ali Zarrabi is an associate professor and principal investigator in the Faculty of Engineering and Natural Sciences, Istinye University, Turkey. Trained as a chemical engineer (BSc and MSc) with a PhD in nanobiotechnology, he leads a research program at the interface of supramolecular chemistry, bioengineering, and nanomedicine to develop smart nano/biomaterials for simultaneous diagnosis and treatment of disease, with a particular focus on nanotheranostics, advanced wound dressings, skin patches, and translational nanomedicine.
Marco Cordani obtained his Ph.D. at the University of Verona, working on the implication of mutated p53 proteins in metabolism and autophagy. Later, he has performed two postdoctoral stays, one at Universidad Autónoma de Madrid (2017) and another at the IMDEA Nanociencia (2018-2020), working on novel nanomedicine and gene editing strategies to counteract cancer. Currently, Postdoctoral Researcher at the University “Claude Bernard Lyon 1, characterizing the involvement of dependence receptors in cell death and metabolism.
"About the title" may belong to another edition of this title.
Revaluation Books
Exeter, United Kingdom
AbeBooks seller since January 6, 2003
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Edward Bowditch Ltd
Exstowe, Exton
Exeter, United Kingdom EX3 0PP
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