Rethinking Cancer: A New Paradigm for the Postgenomics Era
Language: English
Published by Mit Pr, 2025
Series: Book 11 of 17 - Vienna Series in Theoretical Biology
- Softcover
- New
Seller: Revaluation Books, Exeter, United KingdomRevaluation Books
AbeBooks seller since January 6, 2003
Condition: New
£ 81.29
Quantity: 2 available
Add to basketItem description from seller
432 pages. 9.00x7.00x9.00 inches. In Stock.
Seller Inventory # x-0262054345
- Title
- Rethinking Cancer: A New Paradigm for the Postgenomics Era
- Author
- Strauss, Bernhard (Editor)/ Bertolaso, Marta (Editor)/ Ernberg, Ingemar (Editor)/ Bissell, Mina J. (Editor)
- Publisher
- Mit Pr
- Publication year
- 2025
- Condition
- Brand New
- Binding
- Paperback
- Language
- English
- ISBN 10
- 0262054345
- ISBN 13
- 9780262054348
- Item weight
- 0.67 kilograms
- Series
- Book 11 of 17: Vienna Series in Theoretical Biology
Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. Thanks to dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet it is still unclear how to use this knowledge for treatment success. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence.
The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and noncoding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.
"Synopsis" may belong to another edition of this title.
About the Author
Marta Bertolaso is Associate Professor of Philosophy of Science in the Faculty of Engineering at Università Campus Bio-Medico in Rome.
Ingemar Ernberg is Professor of Tumor Biology at the Department of Microbiology, Tumor, and Cell Biology at the Karolinska Institutet in Stockholm.
Mina J. Bissell is Distinguished Scientist in the Biological Systems and Engineering Division at Lawrence Berkeley National Laboratory.
"About the title" may belong to another edition of this title.
Revaluation Books
Exeter, United Kingdom
AbeBooks seller since January 6, 2003
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Edward Bowditch Ltd
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Exeter, United Kingdom EX3 0PP
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