Resistance to Targeted Therapies in Lymphomas

Language: English

Published by Springer, Palgrave Macmillan Sep 2019, 2019

3030244237 / 9783030244231

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This item is printed on demand - Print on Demand Titel. Neuware -Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the understanding of cancer cell biology and its microenvironment which has resulted in the development of biologic agents, also called 'target' therapies. These therapies are more specific in targeting cancer cells either directly or via enhancement of the immune system. Many clinical studies have focused on biological agents in combination with traditional chemotherapy with the goal of improved outcomes, or reduced acute long term complications that are associated with lymphoma therapy.This volume will review different classes of 'target' drugs that have been developed, approved, or are under investigation in the field of lymphoma therapy. The discussion will not only be on the understanding of the mechanisms of action or clinical response of those agents, but will also help the reader to understand the nature of lymphoma biology in patients who relapse or are refractor after exposure to those drugs.Contributors will discuss what is currently known about mechanisms of tumor-related or host-related resistance, and how to overcome this resistance. This understanding is crucial given the dismal outcomes of patients with relapsed or refractory lymphomas. The book provides a unique opportunity to review and reflect on the recent successes and pitfalls of the modern lymphoma therapy era.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 232 pp. Englisch.…

Seller Inventory # 9783030244231

Title
Resistance to Targeted Therapies in Lymphomas
Author
Ana C. Xavier
Publisher
Springer, Palgrave Macmillan Sep 2019
Publication year
2019
Condition
Neu
Binding
Buch
Language
English
ISBN 10
3030244237
ISBN 13
9783030244231
Item weight
518 grams
Dimensions
241x160x19 mm

buchversandmimpf2000

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