Regulation of MHC Class I by Dengue Virus

Language: English

Published by LAP LAMBERT Academic Publishing Apr 2012, 2012

3848495236 / 9783848495238

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -Despite aggressive efforts in dengue research, the control of dengue diseases and discovery of therapeutics against them await complete elucidation of its complex immune-pathogenesis. Virtually all mammalian cells express surface major histocompatibility complex class I (MHC Class I) molecules which are crucial for immune recognition and MHC-restricted cytolysis as part of the adaptive immune response. In contrast to many viruses that escape this host s immune responses by suppressing the MHC Class I pathway, infections by Flaviviruses, such West Nile virus, have been associated with a virus-specific increase of these antigen-presenting molecules. This study presents evidence of MHC Class I gene modulation by dengue virus, hence providing a better understanding of dengue immunopathogenesis that would consequently facilitate the discovery of antiviral therapeutics against dengue. 204 pp. Englisch.

Seller Inventory # 9783848495238

Title
Regulation of MHC Class I by Dengue Virus
Author
Shatrah Othman
Publisher
LAP LAMBERT Academic Publishing Apr 2012
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3848495236
ISBN 13
9783848495238
Item weight
322 grams
Dimensions
220x150x13 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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