Redirection of Th1 and Th2 Responses
Language: English
Published by Springer Berlin Heidelberg Jan 2013, 2013
Series: Book 207 of 322 - Current Topics in Microbiology and Immunology
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 46.45
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -It has been 12 years since the first proposal was made to sub divide mouse CD4 I T cell clones into Th I and Th2 subsets, based on their differences in cytokine production, and 7 years since the first clear demonstration of a similar dichotomy among human T cell clones. In the ensuing period, it has been realized that inappropriate development of Th I or Th2 responses are important features of many immunological and infectious dis eases. Perhaps the first group of diseases to be understood in terms of preferential Th subset activation were allergic diseases (see PARRONC'HI et aI. , this volume). Several of the major, co ordinately regulated, features of allergy, including IgE, eosino philia and mastocytosis, were found to be stimulated by the T- specific cytokines I L-4 and IL-5 and inhibited by the Th I cyto kine, IFN-. This suggested that the presence and severity of al lergic responses reflected the relative numbers of Th I and Th2 cells specific for the offending allergen. Similarly, the very dif ferent consequences of protective Th I and nonprotective Th2 responses to a number of intracellular pathogens have been re cognized for some time (see TRINCHIERI and SCOTI, and COFF MAN et aI. , this volume). 164 pp. Englisch.…
Seller Inventory # 9783662097113
- Title
- Redirection of Th1 and Th2 Responses
- Author
- Sergio Romagnani
- Publisher
- Springer Berlin Heidelberg Jan 2013
- Publication year
- 2013
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3662097117
- ISBN 13
- 9783662097113
- Item weight
- 260 grams
- Dimensions
- 235x155x10 mm
- Series
- Book 207 of 322: Current Topics in Microbiology and Immunology
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BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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