Red Cell Rheology
Language: English
Published by Springer, Springer Okt 1978, 1978
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
AbeBooks seller since January 23, 2017
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This item is printed on demand - Print on Demand Titel. Neuware -Hemolysis during filtration through micropores studied by Chien et al. [I] showed a dependence on pressure gradient and pore diameter that, at the time of publication, did not permit an easy interpretation of the hemolytic mechanism. Acting on the assumption that thresholds of hemolysis are easier to correlate with physical forces than extents of hemolysis, we performed a series of experi ments repeating some of the conditions reported in [I] and then focusing on low L1P in order to define better the thresholds of hemolysis for several pore sizes. Employing a model of a deformed red cell shape at the pore entrance (based on micropipette observations) we related the force field in the fluid to a biaxial tension in the membrane. The threshold for lysis correlated with a membrane tension of 30 dynes/cm. This quantity is in agreement with lysis data from a number of other investigators employing a variety of mechanisms for introduc ing membrane tension. The sequence of events represented here is: a. Fluid forces and pressure gradients deform the cell into a new, elongated shape. b. Extent of deformation becomes limited by the resistance of the cell mem brane to undergo an increase in area. c. Fluid forces and pressure gradients acting on the deformed cell membrane cause an increase in biaxial tension in the membrane. d. When the strain caused by this tension causes pores to open in the membrane, the threshold for hemolysis has been reached [2].Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 444 pp. Englisch.…
Seller Inventory # 9783540090014
- Title
- Red Cell Rheology
- Author
- M. Bessis
- Publisher
- Springer, Springer Okt 1978
- Publication year
- 1978
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3540090010
- ISBN 13
- 9783540090014
- Item weight
- 761 grams
- Dimensions
- 244x170x24 mm
"Synopsis" may belong to another edition of this title.
buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
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