Randomised Clinical Trials
Language: English
Published by John Wiley and Sons Ltd, GB, 2021
- Softcover
- New
Seller: Rarewaves.com USA, London, London, United KingdomRarewaves.com USA
AbeBooks seller since June 11, 2025
Condition: New
£ 103.17
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Add to basketItem description from seller
Seller Inventory # LU-9781119524649
- Title
- Randomised Clinical Trials
- Author
- David Machin, Peter M. Fayers, Bee Choo Tai
- Publisher
- John Wiley and Sons Ltd, GB
- Publication year
- 2021
- Condition
- New
- Binding
- Paperback
- Language
- English
- ISBN 10
- 1119524644
- ISBN 13
- 9781119524649
- Edition
- 2nd Edition
- Item weight
- 988 grams
Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process.
This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority, cluster and stepped wedge trials. Other new chapters describe data and safety monitoring, biomarker studies, and feasibility studies. Updated and expanded sections discuss situations where multiple organs, different body locations or competing risks are involved, subgroup analysis, and multiple outcomes. Written by an author team with extensive experience in conducting clinical trials, this book:
- Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced
- Features several new chapters, updated case studies and examples, and references to changes in regulations
- Explains basic randomised trials, including the parallel two-group controlled trial with a single outcome measure
- Covers paired trial designs and trials with more than two interventions
- Includes a chapter on miscellaneous topics such as adaptive designs, large simple trials, Bayesian methods for very small trials, alpha-spending functions and the predictive probability test
Randomised Clinical Trials is essential reading for clinicians, nurses, data managers, and medical statisticians involved in clinical trials, and for health practitioners responsible for direct patient care in a clinical trial setting.
"Synopsis" may belong to another edition of this title.
About the Author
David Machin, Leicester Cancer Research Group, University of Leicester, UK; and Medical Statistics Group, School of Health and Related Research, University of Sheffield, UK.
Peter M. Fayers, Institute of Applied Health, University of Aberdeen, UK.
Bee Choo Tai, Saw Swee Hock School of Public Health, National University of Singapore, and National University Health System, Singapore; and Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore.
"About the title" may belong to another edition of this title.
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London, London, United Kingdom
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