RP- HPLC Study Of Rebamipide
Language: English
Published by LAP LAMBERT Academic Publishing, 2021
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 39.66
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of the present work was to develop and validate a simple RP-HPLC method for the determination of Rebamipide. Chromatographic separation of Rebamipide was achieved by using a C18 column. A Mobile phase containing a mixture of methanol: water (70:30 v/v) was pumped at the flow rate of 1 ml/min. Detection was performed at 231 nm. Validation parameters were evaluated according to the International Conference on Harmonization (ICH) Q2R1 guidelines. The calibration curve was linear in the concentration range 2- 10mig/ml for the Rebamipide with regression coefficient 0.999. The method was found to be accurate with 0.66 % RSD. RSD values were found to be 0.94 % in the case of intra-day precision studies,whereas0.76% in the case of inter-day precision the limits of detection and quantification were found to be 0.6, 1.98mig/ml, respectively. The results obtained from the stress testing reveals that Rebamipide drug substance is particularly stable under acidic, neutral and thermal degradation conditions. From the stability point of view, care should be taken in the manufacturing process and storage of this product.…
Seller Inventory # 9786203410037
- Title
- RP- HPLC Study Of Rebamipide
- Author
- Biswajit Samantaray
- Publisher
- LAP LAMBERT Academic Publishing
- Publication year
- 2021
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 6203410039
- ISBN 13
- 9786203410037
- Item weight
- 113 grams
- Dimensions
- 220x150x5 mm
"Synopsis" may belong to another edition of this title.
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