Proteomic Strategy for Cancer Biomarker Discovery: Focus on Cancer Specific Proteins for Diagnostic Purposes

Ralph Schiess

ISBN 10: 3838106393 / ISBN 13: 9783838106397

Published by Südwestdeutscher Verlag Für Hochschulschriften, 2009

About this Item

Neu Neuware; original eingeschweisst; Rechnung mit MwSt.; new item, still sealed; -Worldwide over 25 million people have cancer and more than 10 million die from it each year. There is a growing focus on cancer diagnosis because accurate and timely detection of the disease means a better chance for patient survival and lower treatment costs. Today's diagnostic screening methods are often inadequate due to their low accuracy. So far, the high complexity of blood prohibited the sensitive and high throughput profiling of patient sample sets large enough to reliably detect cancer-indicating differences. Yet despite intensive interest and investment, only a few cancer biomarkers are used in clinical practice. This book will give you an overview of the establishment of a new strategy for the discovery, verification and validation of cancer protein biomarkers. Thereby different technological and biological aspects are discussed. Finally, the preliminary results of a prostate cancer study, which resulted in the identification of a panel of new protein biomarker superior to the current standard PSA (prostate specific antigen), are shown. 164 pp. Deutsch.

Seller Inventory # INF1100262105

Bibliographic Details

• Title: Proteomic Strategy for Cancer Biomarker Discovery: Focus on Cancer Specific Proteins for Diagnostic Purposes
• Publisher: Südwestdeutscher Verlag Für Hochschulschriften
• Publication Date: 2009
• Language: German
• ISBN 10: 3838106393
• ISBN 13: 9783838106397
• Binding: Taschenbuch
• Condition: Neu

About this title

Synopsis

Worldwide over 25 million people have cancer and more than 10 million die from it each year. There is a growing focus on cancer diagnosis because accurate and timely detection of the disease means a better chance for patient survival and lower treatment costs. Today’s diagnostic screening methods are often inadequate due to their low accuracy. So far, the high complexity of blood prohibited the sensitive and high throughput profiling of patient sample sets large enough to reliably detect cancer-indicating differences. Yet despite intensive interest and investment, only a few cancer biomarkers are used in clinical practice. This book will give you an overview of the establishment of a new strategy for the discovery, verification and validation of cancer protein biomarkers. Thereby different technological and biological aspects are discussed. Finally, the preliminary results of a prostate cancer study, which resulted in the identification of a panel of new protein biomarker superior to the current standard PSA (prostate specific antigen), are shown.

About the Author

Ralph Schiess, Dr. sc. ETH: Studies in biochemistry at theInstitute of Molecular Systems Biology, ETH Zurich with a focus on mass spectrometrybased proteomics and protein biomarker research, Ph.D. received 2008.