Proteoforms

Xianquan Zhan

ISBN 10: 1838800336 / ISBN 13: 9781838800338

Published by Intechopen Jul 2020, 2020

About this Item

Neuware -A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia.Books on Demand GmbH, Überseering 33, 22297 Hamburg 90 pp. Englisch.

Seller Inventory # 9781838800338

Bibliographic Details

• Title: Proteoforms
• Publisher: Intechopen Jul 2020
• Publication Date: 2020
• Language: English
• ISBN 10: 1838800336
• ISBN 13: 9781838800338
• Binding: Buch
• Condition: Neu
• Dimensions: 266W x 185H x 11D millimeters 266 millimeters width by 185 millimeters height by 11 millimeters depth
• Weight: 418 grams

About this title

Synopsis

A proteoform is the basic unit in a proteome, defined as its amino acid sequence + post-translational modifications + spatial conformation + localization + cofactors + binding partners + a function, which is the final functional performer of a gene. Studies on proteoforms offer in-depth insights and can lead to the discovery of reliable biomarkers and therapeutic targets for effective prediction, diagnosis, prognostic assessment, and therapy of disease. This book focuses on the concept, study, and applications of proteoforms. Chapters cover such topics as methodologies for identifying and preparing proteoforms, proteoform pattern alteration in pituitary adenomas, and proteoforms in leukemia.