Protein-Protein Interactions in Drug Discovery (Methods and Principles in Medicinal Chemistry)
Dömling, Alexander (Editor) / Mannhold, Raimund (Series Editor) / Kubinyi, Hugo (Series Editor) / Folkers, Gerd (Series Editor)
Language: English
Published by Wiley VCH, 2013
- Hardcover
- New
Seller: Revaluation Books, Exeter, United KingdomRevaluation Books
AbeBooks seller since January 6, 2003
Condition: New
£ 157.97
Quantity: 1 available
Add to basketItem description from seller
1st edition. 334 pages. 9.69x6.85x0.87 inches. In Stock.
Seller Inventory # __3527331077
- Title
- Protein-Protein Interactions in Drug Discovery (Methods and Principles in Medicinal Chemistry)
- Author
- Dömling, Alexander (Editor) / Mannhold, Raimund (Series Editor) / Kubinyi, Hugo (Series Editor) / Folkers, Gerd (Series Editor)
- Publisher
- Wiley VCH
- Publication year
- 2013
- Condition
- Brand New
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3527331077
- ISBN 13
- 9783527331079
- Item weight
- 0.86 kilograms
The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the development pipeline of major pharmaceutical companies to illustrate the power and potential of this approach.
From the contents:
* Prediction of intra- and inter-species protein-protein interactions facilitating systems biology studies
* Modulators of protein-protein interactions: The importance of Three-Dimensionality
* Interactive technologies for leveraging the known chemistry of anchor residues
* SH3 Domains as Drug Targets
* P53 MDM2 Antagonists: Towards Non Genotoxic Anticancer Treatments
* Inhibition of LFA-1/ICAM interaction for treatment of autoimmune diseases
* The PIF-binding pocket of AGC kinases
* Peptidic inhibitors of protein-protein interactions for cell adhesion receptors
* The REPLACE Strategy for generating Non-ATP competitive Inhibitors of Cell-Cycle Protein Kinases
and more
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
Revaluation Books
Exeter, United Kingdom
AbeBooks seller since January 6, 2003
Shipping rates from United Kingdom to U.S.A.
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Edward Bowditch Ltd
Exstowe, Exton
Exeter, United Kingdom EX3 0PP
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Business correspondence address: Exstowe, Exton, Exeter, EX3 0PP
Company registration number: 04916632
VAT registration: GB834241546
Authorised representative: Mr. E. Bowditch
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