Protein Phosphatase Protocols

Language: English

Published by Humana Press Mai 1998, 1998

0896034682 / 9780896034686

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -A major mechanism by which cells regulate protein function is to place phosphate groups on serine and threonine residues. Though the steady-state level of protein phosphorylation depends on the relative activities of both kinases and phosphatases, a much greater effort has previously gone into the study of the former that the latter . Today, however, there is an increasing appreciation for the role that protein phosphatases play in the dynamic p- cess of protein phosphorylation . To date, there are four major types of protein serine/threonine phosphatase catalytic subunits, designated protein phosphatase type 1, 2A, 2B, and 2C . Each has been identified by the techniques of protein chemistry and enzymology and can be distinguished from one another by their preference for specific substrates as well as their sensitivity to certain acti- tors and inhibitors . Protein Phosphatase Protocols has been assembled in response to the growing interest these enzymes are receiving . The goal of this compilation is to provide a 'how-to' experimental guide to aid newcomers as well as s- soned veterans in their research endeavors, thus further contributing towards our ever increasing knowledge of serine/threonine phosphatases . What you have before you contains contributions by many of the current and emerging leaders in the field . To highlight just a few, these chapters c- tain step-by-step information on how to isolate novel phosphatases and re- latory subunits, assay for activity, and generate immunological reagents for both biochemical and biological characterization of these enzymes . 336 pp. Englisch.…

Seller Inventory # 9780896034686

Title
Protein Phosphatase Protocols
Author
John W. Ludlow
Publisher
Humana Press Mai 1998
Publication year
1998
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0896034682
ISBN 13
9780896034686
Item weight
591 grams
Dimensions
235x157x23 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

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