Protection & Regeneration Of ¿-cells: Studies Using The Nod Mouse

Language: English

Published by Scholars' Press Aug 2016, 2016

3659839191 / 9783659839191

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This item is printed on demand - Print on Demand Titel. Neuware -Diabetes is a chronic disease affecting approximately 250 million people. To date, transplantation-based therapy is the therapy of choice; however, its success is hampered by the scarcity of transplantable human material. An alternative strategy is the promotion of regeneration in the pancreas. Endothelial progenitor cells (EPCs), a subpopulation of bone marrow (BM) cells, can contribute to tissue repair in various pathological conditions via the formation of new blood vessels. The role and regenerative potential of EPCs in diabetes using non-obese diabetic (NOD) mice, a model of type 1 diabetes (T1D) will be discussed. In addition to promoting endogenous ß-cell regeneration using EPCs, a strategy to protect ß-cell death via apoptosis, using a protease peptide XG-102 developed by Xigen was investigated. In conclusion, our results shown that both therapeutic strategies showed great promise in regenerating the damaged pancreas of NOD mice. While these strategies are still under further investigation, they offer encouragement in the quest for the treatment of early diabetes in the future.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 208 pp. Englisch.

Seller Inventory # 9783659839191

Title
Protection & Regeneration Of ¿-cells: Studies Using The Nod Mouse
Author
Cheen Khoo
Publisher
Scholars' Press Aug 2016
Publication year
2016
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659839191
ISBN 13
9783659839191
Item weight
328 grams
Dimensions
220x150x14 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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