Prognostic Factors in Cancer (Paperback)

Paul Hermanek

ISBN 10: 3540586881 / ISBN 13: 9783540586883

Published by Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin, 1995

Paperback. This monograph is the result of an effort by the International Union Against Cancer (UICC) to study prognostic factors related to cancer. It is an extension of the long-term work on the TNM classification and the strongest prognostic tool for most cancers. The monograph aims to compile information on prognostic factors for most tumour sites and selected tumour types. Each site- or tumour-specific chapter provides a general overview of the relevant literature on prognostic factors. Where possible, the authors have attempted to assess these factors in terms of their clinical relevance and of their strength and independence in influencing prognosis. This compilation represents the first phase of a more extensive process to integrate all prognostic factors in cancer to further enhance the prediction of outcome following treatment. Importance of Prognostic Factors Prognostic factors in cancer often have an immense influence on outcome, while treatment often has a much weaker effect. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9783540586883

Synopsis:

M. K. Gospodarowicz, P. Hermanek, and D. E. Henson Attention to innovations in cancer treatment has tended to eclipse the importance of prognostic assessment. However, the recognition that prognostic factors often have a greater impact on outcome than available therapies and the proliferation of biochemical, molecular, and genetic markers have resulted in renewed interest in this field. The outcome in patients with cancer is determined by a combination of numerous factors. Presently, the most widely recognized are the extent of disease, histologic type of tumor, and treatment. It has been known for some time that additional factors also influence outcome. These include histologic grade, lymphatic or vascular invasion, mitotic index, performance status, symptoms, and most recently genetic and biochemical markers. It is the aim of this volume to compile those prognostic factors that have emerged as important determinants of outcome for tumors at various sites. This compilation represents the first phase of a more extensive process to integrate all prognostic factors in cancer to further enhance the prediction of outcome following treatment. Certain issues surround­ ing the assessment and reporting of prognostic factors are also considered. Importance of Prognostic Factors Prognostic factors in cancer often have an immense influence on outcome, while treatment often has a much weaker effect. For example, the influence of the presence of lymph node involvement on survival of patients with metastatic breast cancer is much greater than the effect of adjuvant treatment with tamoxifen in the same group of patients [5].

Review: "The efforts of the UICC, the editors and contributors are to be commended for publishing this important and progressively evolving scientific endeavour on prognostic assessment" - Cancer Forum

Bibliographic Details

Title: Prognostic Factors in Cancer (Paperback)
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin
Publication Date: 1995
Binding: Paperback
Condition: new