Probability Models for DNA Sequence Evolution
Language: English
Published by Springer New York, Humana Dez 2010, 2010
- Softcover
- New
Seller: buchversandmimpf2000, Emtmannsberg, BAYE, Germanybuchversandmimpf2000
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Condition: New
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This item is printed on demand - Print on Demand Titel. Neuware -Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from 'neutral evolution'. The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication.Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 444 pp. Englisch.…
Seller Inventory # 9781441926777
- Title
- Probability Models for DNA Sequence Evolution
- Author
- Richard Durrett
- Publisher
- Springer New York, Humana Dez 2010
- Publication year
- 2010
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 1441926771
- ISBN 13
- 9781441926777
- Item weight
- 668 grams
- Dimensions
- 235x155x24 mm
- Series
- Book 19 of 35: Probability and Its Applications
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buchversandmimpf2000
Emtmannsberg, BAYE, Germany
AbeBooks seller since January 23, 2017
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