Probability Models for DNA Sequence Evolution

Richard Durrett

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Language: English

Published by Springer New York Aug 2008, 2008

0387781684 / 9780387781686

Series: Book 19 of 35 - Probability and Its Applications

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from 'neutral evolution'. The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication.Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes. 431 pp. Englisch.

Seller Inventory # 9780387781686

Title
Probability Models for DNA Sequence Evolution
Author
Richard Durrett
Publisher
Springer New York Aug 2008
Publication year
2008
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0387781684
ISBN 13
9780387781686
Edition
2nd Edition
Item weight
741 grams
Dimensions
243x164x27 mm
Series
Book 19 of 35: Probability and Its Applications

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany