Prion Diseases

. Ed(s): Baker, Harry F.; Ridley, Rosalind M.

ISBN 10: 1489940405 ISBN 13: 9781489940407
Published by Humana Press Inc., 2013
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Editor(s): Baker, Harry F.; Ridley, Rosalind M. Series: Methods in Molecular Medicine. Num Pages: 319 pages, biography. BIC Classification: PSF. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 18. Weight in Grams: 493. . 2013. Softcover reprint of the original 1st ed. 1996. Paperback. . . . . Books ship from the US and Ireland. Seller Inventory # V9781489940407

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Harry Baker and Rosalind Ridley have done an admirable job in assem­ bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the "prion diseases."

From the Back Cover: In Prion Diseases leading researchers and clinicians describe their state-of-the-art findings and hypotheses arising from a variety of different approaches to this group of diseases. Their approaches include clinical presentations, epidemiology, transgenic methods, and diagnostic tests via transmission electron microscopy and immunoblotting. The diseases covered include human and animal spongiform encephalopathies, such as Creutzfeldt-Jakob disease, mad cow disease, and scrapie.

Prion Diseases illuminates the conflicting hypotheses that have evolved to explain these diverse disorders which can appear as infectious diseases a genetically determined diseases, as well as ones sharing neuropathological similarities with such common neurodegenerative diseases as Alzheimer's disease, Parkinson's disease, and amyotropic lateral sclerosis. It provides a much-needed overview of various approaches to understanding these diseases by showing how researchers have analyzed their different facets, ranging from the epidemiology of the human versions to molecular genetics of the animal forms of the diseases.

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Bibliographic Details

Title: Prion Diseases
Publisher: Humana Press Inc.
Publication Date: 2013
Binding: Soft cover
Condition: New

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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Harry Baker and Rosalind Ridley have done an admirable job in assem bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the 'prion diseases.' Research on prions and the disorders that they cause has progressed relatively rapidly over the last decade since the discovery of the prion protein (PrP) that allowed the application of modem molecular biological and genetic tools. The power of these techniques is awesome and their use in deciphering the once mysterious prion diseases has brought a wealth of new information. Although prions are unprecedented pathogens, appearing to consist only of PrPSc molecules, the diseases that they cause are no less remarkable. The prion diseases in animals include scrapie of sheep and goats as well as 'mad cow' disease or bovine spongiform encephalopathy (BSE). In the United King dom, the epidemic of BSE has heightened public awareness of this previously obscure group of diseases such that any work in the field is likely to stir up interest in the media and become a subject of public debate. It has been diffi cult for British investigators to work on prion diseases without being involved in these controversies. As such, several chapters have been included that deal with political and social issues surrounding prion diseases. The human prion diseases present an equally fascinating saga in which these CNS degenerations present as genetic, sporadic, and infectious illnesses. 336 pp. Englisch. Seller Inventory # 9781489940407

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Taschenbuch. Condition: Neu. Prion Diseases | Rosalind M. Ridley (u. a.) | Taschenbuch | xv | Englisch | 2013 | Humana Press | EAN 9781489940407 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Seller Inventory # 105124210

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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Harry Baker and Rosalind Ridley have done an admirable job in assem bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the 'prion diseases.' Research on prions and the disorders that they cause has progressed relatively rapidly over the last decade since the discovery of the prion protein (PrP) that allowed the application of modem molecular biological and genetic tools. The power of these techniques is awesome and their use in deciphering the once mysterious prion diseases has brought a wealth of new information. Although prions are unprecedented pathogens, appearing to consist only of PrPSc molecules, the diseases that they cause are no less remarkable. The prion diseases in animals include scrapie of sheep and goats as well as 'mad cow' disease or bovine spongiform encephalopathy (BSE). In the United King dom, the epidemic of BSE has heightened public awareness of this previously obscure group of diseases such that any work in the field is likely to stir up interest in the media and become a subject of public debate. It has been diffi cult for British investigators to work on prion diseases without being involved in these controversies. As such, several chapters have been included that deal with political and social issues surrounding prion diseases. The human prion diseases present an equally fascinating saga in which these CNS degenerations present as genetic, sporadic, and infectious illnesses.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 336 pp. Englisch. Seller Inventory # 9781489940407

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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Harry Baker and Rosalind Ridley have done an admirable job in assem bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the 'prion diseases.' Research on prions and the disorders that they cause has progressed relatively rapidly over the last decade since the discovery of the prion protein (PrP) that allowed the application of modem molecular biological and genetic tools. The power of these techniques is awesome and their use in deciphering the once mysterious prion diseases has brought a wealth of new information. Although prions are unprecedented pathogens, appearing to consist only of PrPSc molecules, the diseases that they cause are no less remarkable. The prion diseases in animals include scrapie of sheep and goats as well as 'mad cow' disease or bovine spongiform encephalopathy (BSE). In the United King dom, the epidemic of BSE has heightened public awareness of this previously obscure group of diseases such that any work in the field is likely to stir up interest in the media and become a subject of public debate. It has been diffi cult for British investigators to work on prion diseases without being involved in these controversies. As such, several chapters have been included that deal with political and social issues surrounding prion diseases. The human prion diseases present an equally fascinating saga in which these CNS degenerations present as genetic, sporadic, and infectious illnesses. Seller Inventory # 9781489940407

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