Preclinical Drug Development
Language: English
Published by Taylor & Francis, CRC Press, 2009
Series: Book 45 of 80 - Drugs and the Pharmaceutical Sciences
- Hardcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 278.04
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: Pharmacokinetics Modeling and simulation Formulation and routes of administration Toxicity evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling Screening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.…
Seller Inventory # 9781420084726
- Title
- Preclinical Drug Development
- Author
- Mark Rogge
- Publisher
- Taylor & Francis, CRC Press
- Publication year
- 2009
- Condition
- Neu
- Binding
- Buch
- Language
- English
- ISBN 10
- 1420084720
- ISBN 13
- 9781420084726
- Edition
- 2nd Edition
- Item weight
- 941 grams
- Dimensions
- 254x178x21 mm
- Series
- Book 45 of 80: Drugs and the Pharmaceutical Sciences
Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials.
Highlights of the Second Edition include:
- Pharmacokinetics
- Modeling and simulation
- Formulation and routes of administration
- Toxicity evaluations
- The assessment of drug absorption and metabolism
- Interspecies scaling
- Lead molecule selection and optimization via profiling
- Screening using in silico and in vitro toxicity evaluations
The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
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