The Polymerase Chain Reaction
Language: English
Published by Birkhauser Boston Inc, 1994
- Softcover
- Used
Seller: World of Books Inc, Montgomery, IL, U.S.A.World of Books Inc
AbeBooks seller since March 23, 2026
Condition: Used - Good
£ 10.64
Quantity: 2 available
Add to basketItem description from seller
James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc- ture we had divined from a minimum of experimental data and on theoretical argu- ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. It has not escaped our notice, Francis wrote, that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material. By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act . . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before and, moreover, .…
Seller Inventory # CIN0817637508G
- Title
- The Polymerase Chain Reaction
- Author
- Kary B Mullis
- Publisher
- Birkhauser Boston Inc
- Publication year
- 1994
- Condition
- Good
- Binding
- Paperback
- Language
- English
- ISBN 10
- 0817637508
- ISBN 13
- 9780817637507
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World of Books Inc
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