Osmotically Controlled Oral Drug Delivery

Language: English

Published by LAP Lambert Academic Publishing Jan 2015, 2015

3659133396 / 9783659133398

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -The objective of the study was to develop smotically driven oral drug delivery system of Aceclofenac, to be taken twice daily. It is also objective of present study to evaluate developed osmotic pump. Sodium chloride & sodium bicarbonate were used as an osmogent. The tablets were coated with cellulose acetate as the semipermeable membrane containing castor oil as a plasticizer and microporous membrane was developed by using polyethylene glycol as a plasticizer and pore forming agent.The emipermiable membrane formed by using cellulose acetate as a polymer and castor oil as a plasticizer, allows the passage of water and is selective in nature, which is essential for the zero-order release of drug.The membrane formed by using polyethylene glycol as a plasticizer cannot act as a semipermiable while it behaves as a microporous membrane, which cannot deliver drug not at zero-order. The release rate of drug from microporous membrane is at higher rate than as comparative to semipermiable membrane. It can be conclude from the present study and the results obtained that the osmotic pump for release of Aceclofenac can be developed as a twice a day dosage form.( B.D.) Zero-order release rat 84 pp. Englisch.…

Seller Inventory # 9783659133398

Title
Osmotically Controlled Oral Drug Delivery
Author
Sameer Sheaikh
Publisher
LAP Lambert Academic Publishing Jan 2015
Publication year
2015
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659133396
ISBN 13
9783659133398
Item weight
143 grams
Dimensions
220x150x6 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany