Optimization of Nanoparticles composed Pyridostigmine : Preparation, Evaluation & Optimization

Language: English

Published by LAP LAMBERT Academic Publishing, 2022

6205517426 / 9786205517420

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - The purpose of this book will to prepare Pyridostigmine nanoparticles for control release of Pyridostigmine to improve the oral bioavailability, enhance the solubility and dissolution rate by decreasing particle size of drug. Infrared spectroscopic studies confirmed that there was no interaction between drug and polymers. The controlled release Pyridostigmine nanoparticles were prepared by Solvent evaporation by using Ethyl cellulose, Chitosan & HPMC K100 at different ratios. The production yield of the formulated controlled release nanoparticles (F1 to F16) in the range of 76.11 % to 83.58 %. The drug content of the formulated controlled release nanoparticles (F1 to F16) in the range of 82.56 %to 98.20%. The Theoretical loading of the formulated controlled release nanoparticles (F1- F16) in the range of 24.43 % to 64.24%. The entrapment efficiency increased with increasing the concentration of polymers and the formulations containing chitosan nanoparticles F6 (1:2) showed better entrapment (90.94%) among all formulation.…

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Title
Optimization of Nanoparticles composed Pyridostigmine : Preparation, Evaluation & Optimization
Author
Niwash Kumar
Publisher
LAP LAMBERT Academic Publishing
Publication year
2022
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6205517426
ISBN 13
9786205517420
Item weight
155 grams
Dimensions
220x150x6 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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