Ontwikkeling en evaluatie van slecht oplosbare Rilpivirine door Snedds
Language: Dutch
Published by Uitgeverij Onze Kennis Okt 2020, 2020
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 37.12
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -In dit werk werd een SNEDDS-formulering van een slecht in water oplosbaar geneesmiddel, Rilpivirine, ontwikkeld door gebruik te maken van verschillende polymeren. De oplosbaarheidsstudie werd uitgevoerd om de geschikte olie, oppervlakte-actieve stof en co-surfactant voor Rilpivirine te vinden en er werd een goede oplosbaarheid aangetoond in olie zoals Captex 355, oppervlakte-actieve stof Kolliphor RH 40 en co-surfactieve propyleenglycol. Het medicijngehalte van alle formuleringen werd uitgevoerd. Het maximale medicijngehalte werd gevonden in de formulering F5. De in vitro ontbindingsstudies werden uitgevoerd voor alle vijftien SNEDDS-formuleringen. Het vrijkomen van de vloeibare SNEDDS-formulering F5 was sneller dan de SNEDDS-formuleringen F1 tot en met F15, wat duidt op de invloed van de druppelgrootte op de snelheid van het oplossen van het geneesmiddel. Op basis van een visuele observatietest en een snellere oplossnelheid werd de formulering F5 als geoptimaliseerde formulering afgerond. Het huidige verkennende werk illustreert met succes het potentiële nut van vloeibare SNEDDS-formulering voor het afleveren van een slechte wateroplosbare verbinding zoals Rilpivirine. De resultaten van deze studie tonen het nut aan van SNEDDS voor het verbeteren van de oplosbaarheid en het oplossen van Rilpivirine, wat kan leiden tot betere therapeutische prestaties. 136 pp. Niederländisch.…
Seller Inventory # 9786202580939
- Title
- Ontwikkeling en evaluatie van slecht oplosbare Rilpivirine door Snedds
- Author
- Pamu Sandhya
- Publisher
- Uitgeverij Onze Kennis Okt 2020
- Publication year
- 2020
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- Dutch
- ISBN 10
- 6202580933
- ISBN 13
- 9786202580939
- Item weight
- 221 grams
- Dimensions
- 220x150x9 mm
"Synopsis" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
Shipping rates from Germany to U.S.A.
| Item | 5 to 15 business days | 5 to 15 business days |
|---|---|---|
| First item | £ 19.78 | £ 19.78 |
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- Bank Wire Transfer
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Seller's business information
BuchWeltWeit Ludwig Meier e.K.
Germany
Terms of sale
BuchWeltWeit Inh. Ludwig Meier e.K.
Inhaber: Ludwig Meier
De-Gasperi-Str. 8
51469 Bergisch Gladbach
Deutschland
Tel.: +49(0)22028659300
Fax: +49(0)22028659301
E-Mail: info@buchweltweit.de
Registergericht: Amtsgericht Köln
Registernummer: HRA 28253
Umsatzsteuer-Identifikationsnummer: DE815259907
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