New Chemical Processes with Bismuth(III) Salts

Language: English

Published by LAP LAMBERT Academic Publishing Nov 2011, 2011

3846543934 / 9783846543931

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes several new processes using bismuth(III) reagents and catalysts, with application to steroid chemistry. Two processes for the nucleophilic ring opening of epoxysteroids are presented: one describes the Ritter reaction to afford vic-N-acylamino-hydroxy compounds, whereas the other show that bismuth(III) salts can act both as nucleophiles and reaction promoters, to obtain -substituted-hydroxy steroids. The bismuth(III) salt-catalyzed rearrangement of epoxysteroids is described as a strategy to obtain steroids bearing abnormal ring fusions, inverted configuration at bridgehead stereocenters and methyl groups out of their typical positions, leading to olefinic 19-nor, 18,19-dinor- or 18-norsteroids. The bismuth(III) triflate-catalyzed cleavage of the C17-side chain of corticosteroid allows the easy preparation of highly functionalized 17-ketosteroids. Moreover, full structural elucidation of all the obtained compounds is provided and largely discussed. A general introduction provides the background knowledge to this work. The concept of pharmaceutical green chemistry is discussed in the light of its integration with chemical process within pharmaceutical chemistry. 332 pp. Englisch.…

Seller Inventory # 9783846543931

Title
New Chemical Processes with Bismuth(III) Salts
Author
Rui Miguel de Aguiar Pinto
Publisher
LAP LAMBERT Academic Publishing Nov 2011
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3846543934
ISBN 13
9783846543931
Item weight
512 grams
Dimensions
220x150x20 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany