Nanoengineered Therapeutics for Lung Cancer

Nanoengineered Therapeutics for Lung Cancer: Advanced Drug Delivery Strategies explores contemporary methods for diagnosing and treating lung cancer using cutting-edge nanotechnology. The book provides a foundational understanding of lung cancer biology, detailing innovative nanodrug delivery strategies and their practical applications in treatment. The content is strategically structured, covering the design, synthesis, and application of nanodrug delivery systems. Chapters delve into specific technologies such as gold nanoparticles, exosome-mediated therapies, and siRNA-based gene silencing. The book also addresses challenges like drug resistance and toxicity, offering insights into future research directions and advancements in the field. This book benefits graduate students, researchers, and healthcare professionals by seamlessly integrating theoretical concepts with practical applications. It serves as an essential educational resource, equipping readers with the knowledge and skills needed to tackle complex challenges in lung cancer treatment using nanomedicine. This comprehensive guide ensures that readers stay at the forefront of the rapidly evolving landscape of cancer therapeutics.

• Provides a thorough examination of the design, synthesis, and application aspects of nanodrug delivery systems
• Introduces groundbreaking and advanced methodologies for diagnosing and treating lung cancer
• Highlights how strategic design methodologies significantly enhance therapeutic efficacy, leading to more effective and targeted lung cancer treatments

Arun Kumar Singh is an Assistant Professor in the Department of Pharmacy at University School of Pharmaceutical Sciences, Rayat Bahra University V.P.O. Sahauran, India. He completed his M.Pharm in Pharmaceutics from Galgotias University, Greater Noida. His research interests include nano-formulation, blockchain, IoT, machine learning, artificial intelligence, big data analytics, cancer biology, and neuroscience. He has contributed to academic books and book chapters and has published review articles in the areas of pharmaceutical sciences and healthcare technology. His work focuses on interdisciplinary approaches integrating pharmaceutical research with emerging digital and computational technologies.

Dr. Meenakshi Dhanawat is an Associate Professor at the Amity Institute of Pharmacy, Amity University Haryana, with many years of experience in Pharmaceutical Sciences and Medicinal Chemistry. She completed her Master's degree at NIPER, Mohali, focusing on glycosylamino acids, and earned her Ph.D. from IIT-BHU, Varanasi, investigating CNS drug delivery targeting 5HT1A/2A receptors. Her research encompasses synthetic and heterocyclic chemistry, nanotechnology, drug delivery systems, prodrug design, complexation, polymer chemistry, and herbal drug extraction. Dr. Dhanawat has received notable international recognition, including a travel grant from the AAPS Drug Delivery and Development section for the 2010 National Biotechnology Conference in California, and international travel grants from DBT and DST, Government of India, for conferences in California and Munich. Her distinguished honors include the Rajiv Gandhi National Fellowship, affirming her sustained contributions to pharmaceutical research and academic excellence.

Shikha Baghel Chauhan is Associate Professor in the Department of Industrial Pharmacy at Amity Institute of Pharmacy, Amity University, Noida, India. She has extensive experience spanning academia and the pharmaceutical sector. Her research interests include novel drug delivery systems, transdermal drug delivery, nanocarrier-based formulations, and herbal drug development. In addition to her teaching and research activities, Dr. Chauhan is engaged in scientific publishing and academic outreach, including educational initiatives that support pharmacy education and professional development. She has contributed to the pharmaceutical sciences literature through scholarly publications, books, book chapters, and intellectual property development. Her work focuses on advancing formulation science and drug delivery approaches to address contemporary healthcare challenges.

Dr. Indu Singh is currently serving as an Assistant Professor at the Centre of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh. Previously, she worked as an Assistant Professor in the Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar Central University, Lucknow.

She has over nine years of post-PhD teaching experience and holds a Bachelor of Pharmacy (B. Pharm.), Master of Pharmacy (M. Pharm.), and Doctor of Philosophy (Ph.D.) in Pharmaceutics. She completed her Ph.D. at the National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, under the Government of India, in the area of Nanomedicines specifically on bioconjugated nanotherapeutics for tumor targeting.

A gold medalist in both her B. Pharm. and M. Pharm. programs, Dr. Singh was awarded the GATE and GPAT scholarship by the Ministry of Human Resource Development (MHRD) for her M. Pharm. and the Research Fellowship from the Ministry of Chemicals and Fertilizers, Government of India for her Ph.D. studies. She is a registered pharmacist with the Pharmacy Council of India through the Uttar Pradesh Pharmacy Council, Lucknow.

In 2015, she qualified the Women Scientist-C (WOS-C) examination (KIRAN-IPR) conducted by the Department of Science and Technology (DST), New Delhi. She also received the Young Scientist International Travel Grant from the Council of Scientific and Industrial Research (CSIR), India, to attend the 6th International Conference on Nanomaterials-Research & Application (NANOCON-2014) held in Brno, Czech Republic (EU).

Dr. Singh has received numerous awards for her oral and poster presentations at various national and international conferences. She has published over 70 research papers in reputed international journals with high impact factors, authored 20 book chapters, and written four Scopus-indexed books. Additionally, she has filed four patents, with one patent already granted to her credit. She was the invited speaker for IBRO-APRC Associate School in November 2022.

Dr. Niraj Kumar Jha is an Assistant Professor of Biotechnology at Galgotias University, India, with prior research affiliations at the Centre for Research Impact & Outcome (CRIO), Chitkara University, and Sharda University. His research portfolio encompasses over 200 peer-reviewed articles and scholarly reviews, along with an edited volume published by Springer, reflecting sustained contributions to biomedical research and translational science. According to Scopus metrics, Dr. Jha’s publications have garnered more than 10,000 citations, with an H-index exceeding 50, underscoring the broad impact and visibility of his work within the global scientific community. He is an elected Member of the Royal Society of Biology (MRSB), London, and has been recognized among the World’s Top 2% Scientists in rankings compiled by Elsevier in collaboration with Stanford University. Dr. Jha actively contributes to scientific publishing and peer review as an associate editor for the Journal of Alzheimer’s Disease (IOS Press) and IET Nanobiotechnology (Wiley) and serves on the editorial boards of several international journals, including Scientific Reports. His research is centered on elucidating the molecular and cellular mechanisms underlying complex diseases such as neurodegenerative disorders, cancer, and cardiovascular pathologies. His work particularly emphasizes the modulation of key signaling pathways and explores the therapeutic potential of natural products, phytochemicals, and synthetic small molecules in disease intervention.