NMR Spectroscopy in Drug Development and Analysis
Language: English
Published by Wiley-Blackwell, 1999
- Hardcover
- Used
Seller: MusicMagpie, Stockport, United KingdomMusicMagpie
AbeBooks seller since December 4, 2017
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Add to basketSeller Inventory # U9783527300921
- Title
- NMR Spectroscopy in Drug Development and Analysis
- Author
- Holzgrabe, Ulrike; Wawer, Iwona; Diehl, Bernd
- Publisher
- Wiley-Blackwell
- Publication year
- 1999
- Condition
- Very Good
- Dust jacket
- 48069173
- Signed
- 6/14/2026 6:17:48 PM
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 3527300929
- ISBN 13
- 9783527300921
- Edition
- 1781461068.
- Seller catalogs
- 1, 9783527300921, U
This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging.
In short, this book covers all aspects of drug analysis.
"Synopsis" may belong to another edition of this title.
About the Author
Ulrike Holzgrabe and Iwona Wawer are the authors of NMR Spectroscopy in Drug Development and Analysis, published by Wiley.
"About the title" may belong to another edition of this title.
MusicMagpie
Stockport, United Kingdom
AbeBooks seller since December 4, 2017
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