Mutagenesis and Mitochondrial-Associated Pathologies

Language: English

Published by Intechopen Mai 2022, 2022

1803551712 / 9781803551715

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This item is printed on demand - Print on Demand Titel. Neuware -Reactive oxygen species (ROS) and DNA double-strand breaks can result from mitochondrial defects and external sources, such as ionizing radiation. If not repaired properly, pathogenic mutations are generated. Human diseases resulting from inherited mitochondrial defects manifest in organs that physiologically require a high level of ATP synthesis. These diseases are clinically challenging, but new experimental clinical therapies include gene editing and mitochondrial transplants. Pathogenic ROS-associated cellular damage includes DNA double-strand breaks, and mouse models are now available to study multiple repair pathways. This book discusses the clinical manifestations of mitochondrial diseases in both the eye and the kidney, and presents new insights into double-strand break repair pathways and developmental phenotypes of g-ray-associated ontogenic mutations of Drosophila melanogaste.Books on Demand GmbH, Überseering 33, 22297 Hamburg 116 pp. Englisch.

Seller Inventory # 9781803551715

Title
Mutagenesis and Mitochondrial-Associated Pathologies
Author
Michael Fasullo
Publisher
Intechopen Mai 2022
Publication year
2022
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1803551712
ISBN 13
9781803551715
Item weight
473 grams
Dimensions
266x185x13 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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Impressum Thorsten Retsch Buchversand Mimpf2000 Oberölschnitz 16 95517 Emtmannsberg Deutschland Telefon: 09209-2023188 Email: mimpf2000@online.de USt-ID-Nr.: DE 235096871 Wir führen gebrauchte Bücher aus allen Sparten der Literatur

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