Multimerization strategy to create an artificial pore-forming protein
Language: English
Published by Scholars' Press Sep 2014, 2014
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 39.60
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -Porines generate little or no selective water channels, sometimes voltage-dependent, and several of them play important roles in specific cellular pathways. Through a preliminary bioinformatic analysis was identified a pattern of basic protein with a hairpin structure ( -strand/loop/ -strand) from the PA83 protein of Bacillus anthracis. Through the realization of a very quick and simple experimental protocol we built an artificial construct with seven multimers of the basic module. The experimental plan developed allowed us to obtain in a few days a chimeric protein completely artificial, which was cloned into a bacterial expression vector. Expression experiments has carried out interesting results since we observed that the induced bacterial cultures were less cloudy, indicating a reduced cell growth. In accordance with the recent literature we are inclined to believe that the protein acts like antibiotic, fitting massively in the membrane and causing cell lysis of the host bacteria. This strategy could be used for the production of artificial proteins with biological, pharmaceutical and industrial high-impact. 64 pp. Englisch.…
Seller Inventory # 9783639663006
- Title
- Multimerization strategy to create an artificial pore-forming protein
- Author
- Claudia A. Fichera
- Publisher
- Scholars' Press Sep 2014
- Publication year
- 2014
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3639663004
- ISBN 13
- 9783639663006
- Item weight
- 113 grams
- Dimensions
- 220x150x4 mm
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About the Author
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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BuchWeltWeit Ludwig Meier e.K.
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