Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet

Language: English

Published by LAP LAMBERT Academic Publishing, 2013

3659374008 / 9783659374005

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Bioadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of (a) retaining a dosage form in the G.I tract and (b) increasing the intimacy and duration of contact of drug with the absorbing membrane. In this investigation, natural mucoadhesive materials were isolated from different edible fruits like Aegle marmelos (Linn.) Cor., Zizyphus mauritiana and Tamarindus indica by hot extraction method. Density and swelling property of natural materials were evaluated. Bioadhesive and mucoadhesive qualities of natural materials were evaluated individually by different in vitro testing methods and in vivo X-ray photograph method. It was observed that natural materials have good mucoadhesive property. Mucoadhesive tablets containing 7.5 mg of terbutaline sulphate tablets were prepared by wet granulation method. The sustained release pattern was evaluated by in vitro and in vivo studies. The drug release data were plotted using various kinetic equations (zero order, first order, Higuchi s kinetics.Finally we confirmed our investigation by invitro-invivo correlation study.…

Seller Inventory # 9783659374005

Title
Mucoadhesive Formulation and Evaluation of Terbutaline Sulphate Tablet
Author
Ranabir Chanda
Publisher
LAP LAMBERT Academic Publishing
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659374008
ISBN 13
9783659374005
Item weight
113 grams
Dimensions
220x150x5 mm

AHA-BUCH GmbH

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