Molecularly Imprinted Receptor Targeting Lung Cancer Biomarker

Language: English

Published by LAP LAMBERT Academic Publishing Jul 2014, 2014

365957015X / 9783659570155

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -The early diagnosis of biomarker is crucial for patient survival and successful prognosis of the disease, and for this reason sensitive and specific methods are required for early cancer diagnosis. However, common techniques for separation and concentrating biomarker are not optimal from the viewpoints of sensitivity and selectivity because analyzing these biomarkers from a small amount of serum is difficult due to the complexity of the sample and low levels of these biomarkers. Peptide imprinted polymers were developed for detection of progastrin releasing peptide (ProGRP); a low abundant blood based biomarker for small cell lung cancer. Peptide imprinted polymers with the best affinity characteristics were first identified from a 96-polymer combinatorial libraries. The effects of monomers, crosslinker, porogen, and template on adsorption capacity and selectivity for nonapeptide sequence NLLGLIEAK resulting from tryptic digestion were investigated and optimized. Ultimately, a solid phase extraction method was developed for highly selective enrichment of the target peptide from tryptic digests. 168 pp. Englisch.…

Seller Inventory # 9783659570155

Title
Molecularly Imprinted Receptor Targeting Lung Cancer Biomarker
Author
Abed Abdel Qader
Publisher
LAP LAMBERT Academic Publishing Jul 2014
Publication year
2014
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
365957015X
ISBN 13
9783659570155
Item weight
268 grams
Dimensions
220x150x11 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany