Modulation of HIV Co-Receptor Expression on Cells by Anti-Virals
Language: English
Published by LAP LAMBERT Academic Publishing Jun 2011, 2011
- Softcover
- New
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.
AbeBooks seller since January 11, 2012
Condition: New
£ 43.28
Quantity: 2 available
Add to basketItem description from seller
This item is printed on demand - it takes 3-4 days longer - Neuware -It is the cell surface molecule receptor CD4 and the two chemokine co-receptors CCR5 and CXCR4 that allow the Human Immunodeficiency Virus (HIV) to enter and infect target cells; these are the direct or indirect targets of anti-retroviral drugs (ARV) currently being tested in clinical trials. No characterisation of the potential effect of these drugs on the level of expression of the receptor and/or co-receptors on the cell surface has, as of yet been performed. This is despite the existence of heterologous modulation of at least CCR5 by compounds which are structurally similar to some ARV drugs. We investigated whether candidate microbicides could modulate the expression of CD4, CCR5 and/or CXCR4 on the cell surface membrane of various cell types. Cell lines expressing different or unknown levels of co-receptors were incubated with entry inhibitors, reverse transcriptase inhibitors and protease inhibitors in a time course mode before assessment by flow cytometry. 92 pp. Englisch.…
Seller Inventory # 9783844334241
- Title
- Modulation of HIV Co-Receptor Expression on Cells by Anti-Virals
- Author
- Daniel Y Adu
- Publisher
- LAP LAMBERT Academic Publishing Jun 2011
- Publication year
- 2011
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3844334246
- ISBN 13
- 9783844334241
- Item weight
- 155 grams
- Dimensions
- 220x150x6 mm
"Synopsis" may belong to another edition of this title.
About the Author
"About the title" may belong to another edition of this title.
BuchWeltWeit Ludwig Meier e.K.
Bergisch Gladbach, Germany
AbeBooks seller since January 11, 2012
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| Item | 5 to 15 business days | 5 to 15 business days |
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BuchWeltWeit Ludwig Meier e.K.
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