Modeling of Kinases Inhibitors : 3D-QSAR, Moecular Docking and ADMET : Modeling of Organic Bioactive Molecules Using 3D-QSAR Analysis, Moecular Docking and Preliminary ADMET Evaluation
Language: English
Published by Noor Publishing, 2020
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 32.52
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - The human kinome contains 518 proteins. They share a common mechanism of protein phosphorylation known to play an important role in cellular signaling pathways. Impaired kinase function is recognized to be involved in severe diseases like cancer. The challenge of this PhD work is the in silico identification of potentially interesting molecules concerning the inhibitory process of a set of protein kinases, namely PIM1, PIM2, CDC7, DRAK2 and CAMKIId. The faculty of this protein to interact in differentiation, proliferation and tissue repair phenomena makes their inhibitions crucial for treatments against tumor development in which they are involved. Despites their interests, until now there is no molecule acting on theses kinases has been proven by the Food and Drug Administration. In this way, the authors will focus, in this book on several in silico methods for rational drug design of new kinases inhibitors.
Seller Inventory # 9786202789363
- Title
- Modeling of Kinases Inhibitors : 3D-QSAR, Moecular Docking and ADMET : Modeling of Organic Bioactive Molecules Using 3D-QSAR Analysis, Moecular Docking and Preliminary ADMET Evaluation
- Author
- Mustapha Aouidate
- Publisher
- Noor Publishing
- Publication year
- 2020
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 6202789360
- ISBN 13
- 9786202789363
- Item weight
- 233 grams
- Dimensions
- 220x150x10 mm
"Synopsis" may belong to another edition of this title.
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