4D Modeling and Estimation of Respiratory Motion for Radiation Therapy

Name: 4D Modeling and Estimation of Respiratory Motion for Radiation Therapy
Author: Ehrhardt, Jan|Lorenz, Cristian
ISBN: 9783642446061

Ehrhardt, Jan|Lorenz, Cristian

Language: English

Published by Springer Berlin Heidelberg, 2015

364244606X / 9783642446061

Series: Book 43 of 101 - Biological and Medical Physics, Biomedical Engineering

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Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Deals with the hot topic of pulmonary motion for medical imaging, image processing and therapeutic applicationsGives a cutting edge overview on the topic, written by very notable authors in the fieldAddresses clinical as well as technical r.

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Title: 4D Modeling and Estimation of Respiratory Motion for Radiation Therapy
Author: Ehrhardt, Jan|Lorenz, Cristian
Publisher: Springer Berlin Heidelberg
Publication year: 2015
Condition: New
Binding: Soft cover
Language: English
ISBN 10: 364244606X
ISBN 13: 9783642446061
Series: Book 43 of 101: Biological and Medical Physics, Biomedical Engineering
Seller catalogs: Mathematik/Naturwissenschaften/Technik/Medizin

From the Back Cover

Respiratory motion causes an important uncertainty in radiotherapy planning of the thorax and upper abdomen. The main objective of radiation therapy is to eradicate or shrink tumor cells without damaging the surrounding tissue by delivering a high radiation dose to the tumor region and a dose as low as possible to healthy organ tissues. Meeting this demand remains a challenge especially in case of lung tumors due to breathing-induced tumor and organ motion where motion amplitudes can measure up to several centimeters. Therefore, modeling of respiratory motion has become increasingly important in radiation therapy. With 4D imaging techniques spatiotemporal image sequences can be acquired to investigate dynamic processes in the patient’s body. Furthermore, image registration enables the estimation of the breathing-induced motion and the description of the temporal change in position and shape of the structures of interest by establishing the correspondence between images acquired at different phases of the breathing cycle. In radiation therapy these motion estimations are used to define accurate treatment margins, e.g. to calculate dose distributions and to develop prediction models for gated or robotic radiotherapy. In this book, the increasing role of image registration and motion estimation algorithms for the interpretation of complex 4D medical image sequences is illustrated. Different 4D CT image acquisition techniques and conceptually different motion estimation algorithms are presented. The clinical relevance is demonstrated by means of example applications which are related to the radiation therapy of thoracic and abdominal tumors. The state of the art and perspectives are shown by an insight into the current field of research. The book is addressed to biomedical engineers, medical physicists, researchers and physicians working in the fields of medical image analysis, radiology and radiation therapy.

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