Mg2+ and Excitable Membranes

Language: English

Published by Springer, Springer Berlin Heidelberg Dez 2011, 2011

3642756387 / 9783642756382

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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Softcover

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This item is printed on demand - it takes 3-4 days longer - Neuware -The present book is the outcome of a symposium on magnesium and excitable membranes, held in September 1989 on the occasion of the 12th annual meeting of the European Neuroscience Associ ation in Torino. Leading specialists from around the world met in order to discuss the physiological and clinical effects of magne sium on excitable cells. Magnesium ions are known to playa key role in the regulation of a variety of cell functions and, as such, have been implicated in the control of neuronal excitability and cardiovascular diseases. In the last decade, the advent of new electro physiological techniques has provided important details on the modulatory action of mag nesium on ion channels and the receptor proteins of neurotrans mitters. Thus, in neuronal and muscle cells, extracellular and in is shown to block ion passage through open tracellular magnesium channels in a voltage- and time-dependent manner. The mecha nism appears to be common for voltage- and receptor-operated channels, and it is thought to be an important cofactor in the long-term potentiation of synaptic transmission, brain aging, and cardiac activity. Recent findings show that the action of internal magnesium has additional features. High and low affinity sites for internal magnesium are involved in the regulation of channel gat ings and ion permeation. Biochemical studies suggest that internal magnesium interferes with G-protein subunits, GTP-ase activity, and second messengers involved in channel phosphorylation. 164 pp. Englisch.…

Seller Inventory # 9783642756382

Title
Mg2+ and Excitable Membranes
Author
Piergiorgio Strata
Publisher
Springer, Springer Berlin Heidelberg Dez 2011
Publication year
2011
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3642756387
ISBN 13
9783642756382
Item weight
260 grams
Dimensions
235x155x10 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

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BuchWeltWeit Ludwig Meier e.K.

Germany