Metronidazole Floating Microspheres : Preparation, Evaluation and Optimization of Metronidazole Floating Microspheres

Language: English

Published by LAP Lambert Academic Publishing, 2012

3659312207 / 9783659312205

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Gastroretentive systems can remain in the gastric region for several hours and hence significantly prolong the gastric residence time of drugs. Prolonged gastric retention improves bioavailability, reduces drug waste, and improves solubility for drugs that are less soluble in a high pH environment. Floating microspheres are especially effective in delivery of sparingly soluble and insoluble drugs. It is known that as the solubility of a drug decreases, the time available for drug dissolution becomes less adequate and thus the transit time becomes a significant factor affecting drug absorption. For weakly basic drugs that are poorly soluble at an alkaline pH, hollow microspheres may avoid chance for solubility to become the rate-limiting step in release by restricting such drugs to the stomach.

Seller Inventory # 9783659312205

Title
Metronidazole Floating Microspheres : Preparation, Evaluation and Optimization of Metronidazole Floating Microspheres
Author
Kalpen Patel
Publisher
LAP Lambert Academic Publishing
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659312207
ISBN 13
9783659312205
Item weight
219 grams
Dimensions
220x150x33 mm

AHA-BUCH GmbH

Einbeck, Germany

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