Method development using Back-Scattering Interferometry : Analysis of binding between the adenosine A2A receptor and three selective antagonists
Language: English
Published by AV Akademikerverlag, 2017
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
£ 51.27
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Add to basketItem description from seller
nach der Bestellung gedruckt Neuware - Printed after ordering - Back-scattering interferometry is one of the latest technologies for the study and characterization of interactions between small molecules and more complex drug targets in a native-like environment without any labels or tethers. The information obtained with this technique is of great value since the conditions for the measurement are closest to the real conditions in the body. Principle of signal generation are conformational changes that occur during a binding event between a drug target and its ligand. In this project, the binding interaction between the adenosine A2A receptor and the three antagonists ZM 241385, SCH 58251 and XAC, as well as the agonist (CGS 21680) as positive control was examined. The knowledge about the interactions of the A2AR and its antagonists is of high interest for research of neurological disorders like Parkinson's disease.
Seller Inventory # 9786202200806
- Title
- Method development using Back-Scattering Interferometry : Analysis of binding between the adenosine A2A receptor and three selective antagonists
- Author
- Bianca Schaffrath
- Publisher
- AV Akademikerverlag
- Publication year
- 2017
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 6202200804
- ISBN 13
- 9786202200806
- Item weight
- 227 grams
- Dimensions
- 220x150x9 mm
"Synopsis" may belong to another edition of this title.
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